Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 422, pseudogene (RN7SL422P)

Target
RN7SL422P
Molecular classification
Pseudogene, Non-coding RNA, Other
01

Overview

RN7SL422P is a pseudogene derived from the human 7SL RNA gene, which ordinarily encodes the RNA component of the signal recognition particle (SRP) vital for protein translocation in the endoplasmic reticulum[1][5][7][11]. However, the "422" pseudogene variant is not functional—it does not produce the 7SL RNA and thus is not involved in SRP formation or protein synthesis[1][11]. The vast majority of 7SL pseudogenes are nonfunctional remnants generated by reverse transcription and integration events in the genome[8][9][11]. While some pseudogenes may exert regulatory effects through RNA interference or miRNA binding, there is no direct evidence for such a role in RN7SL422P specifically[2][6]. RN7SL422P should not be considered a receptor, enzyme, transporter, or therapeutic target[1][8][11].

Other names
RN7SL422PRNA, 7SL, cytoplasmic 422, pseudogene(No widely used alternative names beyond official gene symbol)
02

Biological functions

Some pseudogenes can play regulatory roles, such as acting as competitive endogenous RNA (ceRNA) or microRNA spongesMay influence parental gene expression in select biological contextsOther
03

Disease associations

No specific disease associations have been documented for RN7SL422P; the majority of 7SL pseudogenes are not linked to diseaseSome pseudogenes, in general, have been implicated in regulatory processes relevant for disease, but that is not specific to RN7SL422P.Other

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