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RNA, 7SL, cytoplasmic 447, pseudogene (RN7SL447P)

Target: RN7SL447P
Molecular classification: Other, Pseudogene, Non-coding RNA-derived pseudogene

Overview

RN7SL447P is a human pseudogene representing a non-functional, truncated sequence derived from the 7SL RNA gene, which itself encodes the RNA component of the signal recognition particle (SRP). While **7SL RNA** is essential for the cotranslational targeting of secretory and membrane proteins, pseudogenes like RN7SL447P result from the reverse integration of RNA copies back into the genome. These pseudogenes are not transcribed into stable or functional RNA and do not encode proteins. The majority of 7SL RNA-related sequences in the human genome are such pseudogenes and do not have therapeutic relevance[1][6][7].

Other names: RN7SL447PRNA, 7SL, cytoplasmic 447, pseudogene

Mechanism of action

None applicable[1][6].

Biological functions

None for RN7SL447P itself, as pseudogenes generally do not encode functional proteins or RNAs. However, note that the parental 7SL RNA is involved in protein targeting via the SRP complex[3][5].

Disease associations

Other (no known direct role for RN7SL447P specifically). Some pseudogenes can indirectly regulate gene expression or act as miRNA decoys in various diseases, but no such function is established for RN7SL447P[4].

Safety considerations

None known or notable, as there’s no therapeutic targeting or clinical application at present[1][6].

Interacting drugs

None. No known drugs interact with RN7SL447P, as it is not an expressed or functional molecule itself[1][6].

Biomarkers

None known for RN7SL447P[1][6].

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