RNA, 7SL, cytoplasmic 471, pseudogene (RN7SL471P)

RNA, 7SL, cytoplasmic 471, pseudogene (abbreviated as RN7SL471P) is a human pseudogene related to 7SL RNA, a non-coding RNA component of the signal recognition particle (SRP) complex that is essential for protein targeting to the endoplasmic reticulum in eukaryotic cells[1][2][3]. RN7SL471P is not a protein-coding gene and is considered biologically inactive, lacking known function or involvement in cellular signaling, catalysis, or transport, in contrast to its functional relatives (such as RN7SL1-3)[1][4][5][7][9]. 7SL pseudogenes like RN7SL471P are the result of reverse transcription events where 7SL RNA is copied back into the genome but is usually truncated or mutated, precluding a biological function[5][7][9]. Most 7SL-related sequences in the human genome are such pseudogenes, and only a few represent functional 7SL RNA genes[5][7][9]. There are no data supporting its use as a biomarker, drug target, or role in human disease[1][4][6].

Other names

RN7SL471PRN7SL257PRNA, 7SL, cytoplasmic 257, pseudogene