RNA, 7SL, cytoplasmic 516, pseudogene (RN7SL516P)

RN7SL516P is a processed pseudogene of the 7SL cytoplasmic RNA gene in humans. 7SL RNA is the RNA component of the signal recognition particle (SRP) complex, which is critical for targeting proteins to the endoplasmic reticulum during translation. However, RN7SL516P is a pseudogene, meaning it is a non-functional genomic DNA sequence derived from the ancestral functional 7SL RNA gene and does not produce a functional RNA or protein product. Pseudogenes like RN7SL516P generally arise from gene duplication or retrotransposition events and frequently lack regulatory elements or contain disabling mutations such as premature stop codons or truncations[1][6][7]. Some pseudogenes, especially those derived from non-coding RNAs, may be transcribed and have regulatory or decoy functions, for example by acting as miRNA sponges, but no specific function or disease association has been described or validated for RN7SL516P[4]. RN7SL516P is not considered a therapeutic target, does not encode a protein or active RNA, and is not associated with drug interactions, disease, or clinical biomarkers[1][6].

Other names

RN7SL516PRNA, 7SL, cytoplasmic 516, pseudogene

None (pseudogene; not a therapeutic target)