RNA, 7SL, cytoplasmic 535, pseudogene (RN7SL535P)

RN7SL535P (RNA, 7SL, cytoplasmic 535, pseudogene) is a member of the large family of **7SL RNA pseudogenes** found in the human genome[3][5][10]. The functional 7SL RNA is a key component of the **signal recognition particle (SRP)**, an essential ribonucleoprotein complex responsible for directing newly synthesized proteins to the endoplasmic reticulum in eukaryotic cells[7]. However, **RN7SL535P is a non-functional pseudogene**, meaning it is a DNA sequence resembling the 7SL RNA gene but is generally **not transcribed into a functional RNA or protein product**[3][5][10]. Pseudogenes such as RN7SL535P are considered genomic relics originating from reverse transcription events or sequence duplications and are typically **not involved in normal physiology or disease mechanisms**[4][7].[1][3][5][10][11].\n\nA notable feature of the 7SL RNA family is its evolutionary origin from the SRP RNA, which is highly conserved and forms the RNA backbone of the signal recognition particle[7]. In humans, only a few loci encode functional 7SL RNA, whereas **hundreds of loci**, such as RN7SL535P, exist in the genome as pseudogenes[7][3][5]. These pseudogenes do not encode proteins and mostly lack regulatory elements necessary for expression[4]. Some pseudogenes in other contexts have been shown to regulate gene expression, but no such evidence is available for RN7SL535P itself[2][4].

Other names

RN7SL535P