RNA, 7SL, cytoplasmic 605, pseudogene (RN7SL605P)

**RNA, 7SL, cytoplasmic 605, pseudogene (RN7SL605P)** is a human pseudogene derived from the 7SL RNA, which is the non-coding RNA component of the signal recognition particle (SRP). The SRP is essential for targeting newly synthesized proteins to the endoplasmic reticulum, but the pseudogenes (including RN7SL605P) are non-functional copies within the genome that do not produce an active RNA product necessary for SRP activity[1][5]. Instead, 7SL pseudogenes like RN7SL605P are thought to arise via reverse transcription from mature RNAs and are present in many truncated forms[5]. While pseudogenes can sometimes have regulatory roles at the RNA level (e.g., by acting as competitive endogenous RNAs, producing siRNAs, or interacting with RNA-binding proteins), there is no evidence that RN7SL605P is a therapeutic target, encodes a protein, or plays a direct functional role in disease[4][5][6]. Its primary relevance is as a genomic remnant related to the functional 7SL RNA gene. **Key points:** - This entity is a **pseudogene** and not a therapeutic target, enzyme, receptor, transporter, or functional protein. - No drugs, mechanisms of action, or direct biomarker or safety implications are associated with RN7SL605P. - It has sequence similarity to functional 7SL RNA, but its primary utility is genomic annotation and evolutionary study[5]. If more information about the functional 7SL RNA or the broader SRP complex is needed, this can be provided separately.

Other names

RN7SL605P7SL RNA pseudogene7SL pseudogenesignal recognition particle RNA pseudogene