Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 717, pseudogene (RN7SL717P)

Target
RN7SL717P
Molecular classification
Pseudogene, Non-coding RNA pseudogene
01

Overview

RN7SL717P (RNA, 7SL, cytoplasmic 717, pseudogene) is a non-coding RNA pseudogene in the human genome. It is derived from the functional 7SL RNA gene, which is part of the signal recognition particle (SRP) complex that regulates protein targeting to membranes. Unlike functional 7SL RNA genes, RN7SL717P does not encode an active RNA or protein and is characterized by sequence similarity with functional SRP genes but lacks the ability to produce a functional product due to mutations, truncations, or the absence of necessary regulatory elements[1][2][5][6]. Pseudogenes such as RN7SL717P arise via direct duplication, retrotransposition, or other genomic processes but generally have no active biological function and are not considered meaningful molecular targets in therapy or diagnostics. If you need information on the functional 7SL RNA (not the pseudogene), it is involved in the SRP complex for directing nascent proteins to the endoplasmic reticulum and has established biological roles and disease relevance[3][4]. However, RN7SL717P itself does not share these characteristics.

Other names
RN7SL717PRNA, 7SL, cytoplasmic 717, pseudogene
02

Mechanism of action

None applicable; no known drug targets this pseudogene.

03

Biological functions

None established for RN7SL717P itself. By definition, pseudogenes are nonfunctional, although rare cases of pseudogenes exerting regulatory effects exist[2].The functional 7SL RNA is a structural component of the signal recognition particle and is involved in protein translocation, but that does not apply to RN7SL717P[3][4].
04

Disease associations

None demonstrated for RN7SL717P; pseudogenes typically lack disease associations unless they acquire a regulatory or pathological role, which is not described in the literature for this entry[1][2].
05

Safety considerations

None reported; pseudogenes do not typically pose safety or therapeutic challenges.

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