RNA, 7SL, cytoplasmic 725, pseudogene (RN7SL725P)

RNA, 7SL, cytoplasmic 725, pseudogene (RN7SL725P) is a *processed pseudogene* in the human genome, highly similar to the functional 7SL RNA gene but lacking protein-coding or regulatory activity due to truncations and mutations[1][5]. The parental 7SL RNA is an essential non-coding RNA of the Signal Recognition Particle, involved in targeting secretory proteins to the endoplasmic reticulum in eukaryotic cells[3][7][9]. The genome contains hundreds of 7SL-like pseudogenes generated by reverse transcription and sequence integration, but only a small number encode functional RNAs[5]. RN7SL725P and similar pseudogenes are generally transcriptionally inactive or produce nonfunctional RNA fragments[1][8]. Some processed pseudogenes may theoretically regulate parental gene expression through ceRNA/miRNA sponge mechanisms, but there is no evidence that RN7SL725P is active in this way[4].

Other names

RN7SL725P7SL pseudogeneRNA, 7SL pseudogene