Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 76, pseudogene (RN7SL76P)

Target
RN7SL76P
Molecular classification
Pseudogene, Non-coding RNA
01

Overview

RN7SL76P is a non-coding RNA pseudogene in the human genome, belonging to the **7SL RNA pseudogene family**[1][6][7]. The canonical functional gene in this family is **RNA, 7SL, cytoplasmic 1** (RN7SL1), which is a critical RNA component of the signal recognition particle (SRP), essential for co-translational targeting of proteins to the endoplasmic reticulum membrane[3][5]. Pseudogenes like RN7SL76P result from **duplication or reverse transcription events** and generally do **not encode a functional product nor serve a direct biological function**[4][6][7]. There are many 7SL RNA pseudogenes in the human genome; these are **defective, truncated, or otherwise nonfunctional sequences** derived from ancestral RNA genes[6][7].\n\nIs there something wrong with this target?\nYes:\n- There is **no evidence RN7SL76P encodes a functional protein or RNA with specific biological activities**[6][7][4].\n- It is a **pseudogene**, not an enzyme, receptor, transporter, or an established therapeutic target.\n- The information is limited and there is no indication of disease association, drug interaction, biomarker role, or safety/therapeutic application.\n\nAdditional context:\n- **7SL RNA** is the functional RNA in the SRP complex but RN7SL76P is a nonfunctional copy/pseudogene[3][6][7].\n- Pseudogenes can sometimes be transcribed, and in rare cases, certain pseudogenes have regulatory roles[2], but there is no evidence this specific pseudogene (RN7SL76P) is functional or clinically relevant.\n- Pseudogenes, including 7SL pseudogenes, are common across the genome, often derived from retrotransposition and largely considered genomic "fossils" without active roles[4][6][7].\n\nSummary:\nRN7SL76P is a non-coding, non-functional pseudogene derived from the 7SL RNA family, with no established biological, clinical, or pharmacological roles, and should **not be considered a therapeutic target**.

Other names
RN7SL76P

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