Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 778, pseudogene (RN7SL778P)

Target
RN7SL778P
Molecular classification
Pseudogene, Noncoding RNA (by origin, but not in function), Other
01

Overview

RN7SL778P (RNA, 7SL, cytoplasmic 778, pseudogene) is a nonfunctional genomic DNA sequence that resembles the 7SL RNA gene. 7SL RNA is a conserved noncoding RNA component of the signal recognition particle (SRP), important for co-translational targeting of nascent proteins to the endoplasmic reticulum. RN7SL778P, like other 7SL RNA pseudogenes, arises from reverse transcription and genomic integration of RNA, resulting in truncated, nonfunctional copies. These pseudogenes do not produce active RNA or protein products, and are not considered as receptors, enzymes, or classical drug targets. They may have indirect roles in genome evolution, tissue-specific expression, or acting as competing endogenous RNAs (ceRNAs) in some contexts, but there is no evidence that RN7SL778P itself has functional or therapeutic relevance[1][6][4][2]. This entry, RN7SL778P, is a pseudogene—not a gene, not a receptor, and not a therapeutic target[1][4][6]. Most annotations in therapeutic databases or target lists are either missing or not applicable for this entity. The functional counterpart, 7SL RNA, has important regulatory and structural roles in protein targeting and some disease links, but these do not apply to the RN7SL778P pseudogene itself[3][5][1][6].

Other names
RN7SL778PRNA, 7SL, cytoplasmic 778, pseudogene
02

Biological functions

Other (pseudogenes do not have classic biological functions; functional 7SL RNA is architectural in the signal recognition particle, but RN7SL778P does not encode active RNA)
03

Disease associations

Other (RN7SL778P itself is not implicated in direct disease roles; broader 7SL RNA pseudogenes may participate in regulatory networks affecting cancer and cellular response, but RN7SL778P has no known association)

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