RNA, 7SL, cytoplasmic 797, pseudogene (RN7SL797P)

RN7SL797P is a human pseudogene locus derived from the 7SL RNA gene, which normally encodes the RNA component of the signal recognition particle—a ribonucleoprotein required for co-translational protein targeting to the endoplasmic reticulum. As a pseudogene, RN7SL797P has lost its canonical function due to truncation or mutation and is not transcribed into a functional RNA capable of participating in SRP-mediated protein trafficking. Most 7SL RNA-like loci in the human genome are inactive pseudogenes produced by retrotransposition or duplication events and do not encode active RNA species. Unlike functional 7SL RNA, which is an architectural and regulatory core of the SRP complex and is involved in halting ribosomal translation and protein translocation, RN7SL797P and similar pseudogenes lack the necessary sequence and structure for these biological roles. While certain pseudogenes are capable of producing regulatory RNAs or functioning in epigenetic and post-transcriptional gene regulation, no clear evidence supports any disease relevance or regulatory role for RN7SL797P specifically. If you require structured information mapping for clinical or pharmacological databases, RN7SL797P should be excluded as a therapeutic target. If the focus is on regulatory pseudogenes broadly, only then might transcriptomic or epigenetic roles be considered—however, these remain speculative for this locus.

Other names

RN7SL797PRNA, 7SL, cytoplasmic 797 pseudogene

Not applicable (no drugs target this pseudogene)