RNA, 7SL, cytoplasmic 8, pseudogene (RN7SL8P)

RN7SL8P (RNA, 7SL, cytoplasmic 8, pseudogene; 7L63) is a non-protein-coding pseudogene in the human genome resulting from retroposition of the functional 7SL RNA gene. The functional 7SL RNA is a key component of the signal recognition particle, which is responsible for targeting proteins to the endoplasmic reticulum and regulating translation[1][3]. In contrast, RN7SL8P is a truncated and likely inactive copy, lacking biological function and significance as a therapeutic target. Human DNA contains hundreds of 7SL RNA pseudogenes of diverse structures, which are not expressed and serve only as genomic relics[4]. Disambiguation context: - Sometimes, “7SL RNA pseudogenes” are mistaken for the active 7SL RNA gene (RN7SL1), which has central roles in protein synthesis, secretion, and has been implicated in cancer biology and viral replication[1][3]. RN7SL8P does not have these roles and should not be conflated with the functional molecule. If you need information on the functional molecule, search for “7SL RNA” or “Signal recognition particle RNA,” not its pseudogenes.

Other names

7L63RNA, 7SL, cytoplasmic 8, pseudogeneRN7SL8P