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Target intelligence / Profile preview
RNA, 7SL, cytoplasmic 815, pseudogene (RN7SL815P)
- Target
- RN7SL815P
- Molecular classification
- Other (classified as a small non-coding RNA pseudogene; specifically, a pseudogene of the 7SL RNA family)
01
Overview
RNA, 7SL, cytoplasmic 815, pseudogene (RN7SL815P) is a human pseudogene representing a non-functional, truncated genomic copy of the 7SL RNA gene. The 7SL RNA family encodes the RNA component of the signal recognition particle, which is crucial in directing the localization of nascent proteins. Most 7SL-like loci in the genome, including RN7SL815P, are generated by retrotransposition and do not produce functional RNA. RN7SL815P is formally recognized by genetic nomenclature committees but is not believed to encode an active product. It has no direct functional or disease relevance but has shown association, via copy number variants, with clinical outcomes in prostate cancer, likely as a genomic marker rather than a functional effector.
- Other names
- RN7SL815P
02
Mechanism of action
None. No known mechanisms, given the lack of evidence for a protein or functional RNA product.
03
Biological functions
Other (as a pseudogene, RN7SL815P does not have an assigned biological function; functional 7SL RNA is involved in protein targeting within cells via the signal recognition particle, but pseudogenes are generally non-functional copies)
04
Disease associations
Other (Copy number gains of this pseudogene have shown a statistical association with worse survival in prostate cancer cohorts analyzed by multi-omics, but there is no evidence for a direct functional or pathogenic role for RN7SL815P itself)
05
Safety considerations
None known. No therapeutic manipulation is established for this pseudogene, and there are no safety concerns described in the literature.
06
Interacting drugs
None known. There are no drugs or small molecules reported to interact with RN7SL815P or its product, as it is a pseudogene.
07
Biomarkers
Copy number gain of RN7SL815P is reported as a prognostic biomarker for worse survival in prostate cancer in certain multi-omic studies.
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