Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 827, pseudogene (RN7SL827P)

Target
RN7SL827P
Molecular classification
Pseudogene, Non-coding RNA pseudogene, Other
01

Overview

RNA, 7SL, cytoplasmic 827, pseudogene (RN7SL827P) is a human pseudogene derived from the 7SL RNA gene, part of the signal recognition particle (SRP) RNA family[1][2][3]. As a pseudogene, RN7SL827P is a non-coding segment of DNA that closely resembles the functional 7SL RNA gene but is generally nonfunctional in terms of producing a stable or biologically active RNA product[2][6]. While most 7SL-derived pseudogenes do not yield functional RNA, some pseudogene transcripts can have regulatory roles, such as acting as microRNA (miRNA) decoys or being processed into small interfering RNAs (siRNAs) that modulate expression of other genes through RNA interference[4]. However, there is no evidence that RN7SL827P functions as a therapeutic target, nor are there reports of drug interactions or use as a biomarker. Its role, if any, would likely be confined to potential regulation of gene expression at the RNA level within specific contexts, but this is not established for this particular pseudogene[2][4][6].

Other names
RN7SL827PRNA, 7SL, cytoplasmic 827, pseudogene
02

Biological functions

Possible regulation of gene expression through RNA interferencePossible miRNA decoyLimited or no direct functional activity as gene product
03

Disease associations

Other (pseudogene deregulation is implicated in cancer and may have roles as regulatory RNA in some contexts, but there is no specific disease association for RN7SL827P)

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