Target intelligence / Profile preview

RNA, U1 small nuclear 107, pseudogene (RNU1-107P)

Target
RNU1-107P
Molecular classification
Pseudogene, Small nuclear RNA (snRNA)–related, Non-coding RNA
01

Overview

RNU1-107P corresponds to a pseudogene related to the U1 small nuclear RNA (snRNA) family, which is essential for the accurate splicing of pre-mRNA in human cells. Unlike the canonical U1 snRNA loci (e.g., RNU1-1), U1 snRNA pseudogenes such as RNU1-107P possess sequence similarity but are generally considered nonfunctional due to mutations, deletions, or other sequence changes that disrupt canonical processing. While some pseudogenes are transcriptionally active and can regulate gene expression via RNA mechanisms, RNU1-107P itself is not known to encode a functional snRNA or play a direct biological role. It has not been associated with human disease or targeted therapeutically. The locus is annotated for comparative genomics, gene expression, and snRNA sequence diversity studies[1][5]. RNU1-107P is accurately classified as a pseudogene—not a therapeutic target, receptor, enzyme, or molecule relevant to drug development. Any designation of RNU1-107P as a druggable or pharmacological target would be incorrect[1][5].

Other names
RNU1-107PU1 small nuclear RNA pseudogene 107
02

Mechanism of action

None; not applicable.

03

Biological functions

None confirmed for RNU1-107P itself; related U1 snRNA is involved in pre-mRNA splicing and transcriptome regulationSome U1 pseudogenes can be transcriptionally active and possibly regulate processing of specific pre-mRNAs in a cell type–specific manner, but no specific data is available for RNU1-107P
04

Disease associations

None clearly established for RNU1-107P itselfU1 snRNA sequence/loci have been studied with respect to genome instability and mutation load in cancer, but RNU1-107P specifically is not reported as a disease gene

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