RNA, U1 small nuclear 43, pseudogene (RNU1-43P)

**RNA, U1 small nuclear 43, pseudogene (RNU1-43P)** is a human non-coding RNA gene classified as a pseudogene[4][1][6]. As a U1 small nuclear RNA pseudogene, it is related by sequence and nomenclature to genes encoding **U1 snRNA**—a key component of the spliceosome machinery which is essential for pre-mRNA splicing—but RNU1-43P itself is not thought to encode a functional RNA product[4][6]. There is no evidence it produces protein or has an active biological role; it is annotated as a **pseudogene** without documented function or disease association, drug interactions, or known roles in disease biology[1][4][6]. **Clarification**: - *Therapeutic Target Status*: RNU1-43P is not considered a therapeutic target, receptor, enzyme, transporter, or functional gene—it is a pseudogene and has no proven biological function or drug interaction profile[1][4][6]. - *Potential for Confusion*: It is important not to confuse this gene with its functional counterparts such as RNU1-1 (RNA, U1 small nuclear 1), which is an essential component of the spliceosome[2][7][8]. - *Gene Nomenclature*: The official full name and approved symbol are provided by HGNC (HUGO Gene Nomenclature Committee)[4]. - *Function*: No function or disease mechanism is available for this gene in major gene function databases[6].

Other names

RNU1-43P