RNA, U1 small nuclear 61, pseudogene (RNU1-61P)

RNU1-61P, also known as "RNA, U1 small nuclear 61, pseudogene," is a non-coding RNA classified as a pseudogene related to U1 small nuclear RNA (snRNA). U1 snRNAs are essential components of the spliceosome complex, responsible for recognition of 5′ splice sites during pre-mRNA splicing and safeguarding nascent transcripts from premature polyadenylation. However, as a **pseudogene**, RNU1-61P is generally considered non-functional: it does not produce a mature, active RNA molecule and is not assembled into functional spliceosomal units. Many U1 snRNA pseudogenes and variant loci exist throughout the genome and can sometimes be transcribed, but they typically lack the necessary sequence elements for full biogenesis or interaction with spliceosomal proteins[2]. There is no evidence that RNU1-61P serves as a therapeutic, diagnostic, or pharmacological target, nor are there known drugs or safety concerns associated with it[4].

Other names

RNU1-61PU1 snRNA pseudogene 61