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RNU1-75P is a human gene described as “RNA, U1 small nuclear 75, pseudogene.” It belongs to the large family of pseudogenes derived from the U1 small nuclear RNA (U1 snRNA) genes, which are normally a vital component of the spliceosome complex. The canonical U1 snRNA (from functional RNU1 genes) mediates 5′ splice site recognition and plays a crucial role in pre-mRNA splicing and regulating transcriptome integrity, but the RNU1-75P locus itself is a pseudogene, meaning it does not encode a functional RNA product and is presumed to lack normal biological function[3][4][5]. No data are available that suggest RNU1-75P functions as a therapeutic target, serves as a biomarker, or interacts with drugs. It is annotated in gene databases (GeneCards, AllianceGenome, NCBI Gene) as a non-functional pseudogene, meaning it is not expected to participate in recognized molecular or cellular processes[3][4][5].
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