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RNA, U11 small nuclear 3, pseudogene (RNU11-3P)
- Target
- RNU11-3P
- Molecular classification
- Pseudogene, Noncoding RNA (as a lineage, but the pseudogene is not itself a functional RNA)
01
Overview
RNA, U11 small nuclear 3, pseudogene (RNU11-3P) is a human genomic sequence classified as a pseudogene of the functional U11 small nuclear RNA gene. The U11 snRNA is part of the minor spliceosome complex involved in pre-mRNA splicing, but RNU11-3P itself is a nonfunctional copy and does not encode any active molecule[1][5][8]. Pseudogenes are typically formed via gene duplication or retrotransposition and accumulate mutations that prevent the production of functional protein or RNA[2][4]. RNU11-3P is cataloged in databases like NCBI (Gene ID: 106479562) and Ensembl (ENSG00000212413), and resides on chromosome 10[5][8]. There is currently no evidence that RNU11-3P participates in cellular regulation, disease mechanisms, or serves as a biomarker or drug target.
- Other names
- RNU11-3PRNA, U11 small nuclear 3, pseudogene
02
Mechanism of action
None. No drug mechanisms of action pertain to this pseudogene
03
Biological functions
Other. Pseudogenes typically do not have direct biological functions; however, emerging research highlights that some pseudogenes can act in regulatory roles, for example as competing endogenous RNAs (ceRNAs) or microRNA sponges in rare cases (but no evidence for RNU11-3P specifically)
04
Disease associations
Other. Specific disease associations are not documented for RNU11-3P. Functional U11 snRNA has been linked to certain pituitary tumors and may serve as a biomarker, but this does not extend to the pseudogene
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