RNA, U4 small nuclear 11, pseudogene (RNU4-11P)

RNU4-11P, formally known as RNA, U4 small nuclear 11, pseudogene, is annotated as a **pseudogene** of the U4 small nuclear RNA gene family[1]. Pseudogenes are segments of DNA that resemble known genes but are generally nonfunctional due to mutations or truncations and are typically not transcribed into active RNA or protein. The canonical functional U4 small nuclear RNA (such as RNU4-2) is an essential component of the **spliceosome complex**, required for proper pre-mRNA splicing, and variants in functional U4 snRNA genes have been directly implicated in neurodevelopmental disorders, but there is no evidence to suggest that this particular pseudogene (RNU4-11P) is transcribed, produces functional RNA, or acts as a **therapeutic target**[1]. No biological function, disease association, drug interaction, biomarker value, or therapeutic potential has been described for RNU4-11P. The entry is considered **incorrect as a therapeutic target** because pseudogenes by definition lack canonical function and therapeutic relevance in most cases, and no current evidence supports a functional or disease-association role for RNU4-11P[1]. If a functional U4 snRNA variant (such as RNU4-2) is intended, further clarification is needed, as only functional snRNA genes—not pseudogenes—have described roles in human disease and biology[3][4][5].

Other names

RNU4-11P