RNA, U4 small nuclear 72, pseudogene (RNU4-72P)

**RNA, U4 small nuclear 72, pseudogene (RNU4-72P)** is a *pseudogene* that contains sequence similarity to the functional U4 small nuclear RNA gene, but by definition, as a pseudogene, it does **not encode a functional RNA product** and is *not involved in known biological or pathological roles*. The pseudogene structure is notable for having high sequence similarity to U4 snRNA but is non-functional and often flanked by direct repeats in the genome. Pseudogenes like this may arise from retrotransposition or gene duplication events and subsequent loss of function[1][3]. There is no evidence that RNU4-72P serves as a direct target for drugs, participates in disease pathways, or is a functional biomolecule relevant for therapeutic intervention. This is distinct from functional RNU4 genes (such as RNU4-2), which encode essential components of the spliceosome[6][4]. **Clarification:** There is **something wrong with this target as written for most biomedical/therapeutic contexts**: it is a *pseudogene*—not a functional gene, receptor, or therapeutic target. The true, disease- and splicing-relevant entity is the canonical U4 snRNA gene, such as RNU4-2, rather than a pseudogene like RNU4-72P[1][3][6].

Other names

RNU4-72PU4 pseudogeneRNA, U4 snRNA pseudogeneU4 small nuclear pseudogene