RNA, U4 small nuclear 92, pseudogene (RNU4-92P)

RNU4-92P is an annotated pseudogene in the human genome for the U4 small nuclear RNA[4][7]. Unlike the functional RNU4-2 gene, which encodes U4 snRNA required for spliceosome activity and is implicated in neurodevelopmental disorders, RNU4-92P is not transcribed into a functional RNA, nor does it partake in pre-mRNA splicing. There are no known biological functions, disease associations, or therapeutic applications for RNU4-92P. Most available information about U4 snRNA pseudogenes comes from comparative genomics, with evidence that such pseudogene copies exist in multiple species and are usually truncated or lack regulatory elements required for expression[7]. The recent surge in clinical and functional studies of U4 snRNA is centered on its active gene (RNU4-2), not the pseudogene RNU4-92P.

Other names

RNU4-92P