RNA, U6 small nuclear 1105, pseudogene (RNU6-1105P)

RNU6-1105P is a processed pseudogene derived from the U6 small nuclear RNA gene family. U6 snRNA is a functional non-coding RNA that participates in pre-mRNA splicing as part of the spliceosome complex, specifically facilitating intron excision and ligation of exons in eukaryotic cells. The U6 snRNA is among the most evolutionarily conserved RNA species involved in splicing, highlighting its critical catalytic role in mRNA maturation.\n\nPseudogenes of U6 snRNA, such as "RNU6-1105P," are widespread in vertebrate genomes. They typically arise through retrotransposition mechanisms mediated by LINE elements (e.g., L1). These sequences:\n- Lack promoter and regulatory regions needed for expression,\n- Accumulate mutations or truncations,\n- Are not known to be transcribed or functionally active.\n\nThere is no evidence that RNU6-1105P or similar U6 snRNA pseudogenes are involved in signal transduction, cellular processes, or disease mechanisms; nor do they act as therapeutic targets, biomarkers, or interact with drugs. If your focus is on drug targets or biological activity, this entry is incorrect, as RNU6-1105P itself is not a protein, receptor, enzyme, or functional RNA.\n\nIf you intended to refer to the canonical, active U6 snRNA (not the pseudogene), that entity is classed as a non-coding snRNA and is critical for spliceosome function and RNA splicing, but still not considered a drug target by itself.

Other names

RNU6-1105PRNA, U6 small nuclear 1105, pseudogene