RNA, U6 small nuclear 1106, pseudogene (RNU6-1106P)

The RNU6-1106P pseudogene is a processed pseudogene originating from the U6 small nuclear RNA gene family, which encodes components central to the spliceosome—the cellular machinery responsible for pre-mRNA splicing[1][4][5][3]. Unlike functional U6 snRNA genes, pseudogenes such as RNU6-1106P are typically nonfunctional copies, produced via retrotransposition events mediated by LINE (long interspersed nuclear element) activity, often recognized by the lack of intronic sequences and sequence mismatches[4]. Pseudogenes can contribute to genomic diversity, and although some pseudogenes in other families have been implicated in regulatory roles or as sources of small interfering RNAs, there is no specific evidence or function attributed to RNU6-1106P[4][6]. RNU6-1106P is not considered a therapeutic target, receptor, enzyme, transporter, or transcription factor. It is a molecular remnant without an established biological or disease role, no known drug interactions, mechanisms, or safety concerns, and is not used as a biomarker for any disease state[1][4][5]. Key assessment: - This entry is not a functional biological target but a processed pseudogene; therefore, it is *not* utilized as a therapeutic or diagnostic target[1][4]. - The entry appears correctly spelled, but its biological relevance is limited by its nonfunctional, pseudogene status and should be flagged as is_incorrect: true for targeting purposes.

Other names

RNU6-1106PU6 snoRNA 1106 pseudogeneU6-1106 pseudogene