RNA, U6 small nuclear 1110, pseudogene (RNU6-1110P)

RNU6-1110P designates a **pseudogene** corresponding to the U6 small nuclear RNA (snRNA). U6 snRNAs are non-coding RNAs essential for pre-mRNA splicing, functioning as integral components of the spliceosome; however, pseudogenes such as RNU6-1110P are non-functional genomic loci that bear sequence similarity to bona fide U6 snRNA genes but are not transcribed into active, functional RNA[3][4][5]. Pseudogenes can arise by retrotransposition, gene duplication, or genomic rearrangements, and in the case of U6 snRNA, large numbers of these pseudogenes are found in the human and other vertebrate genomes, providing a record of retrotransposition events but no known regulatory or structural function[4][5]. **Key clarifications:** - The primary functional unit is the U6 small nuclear RNA, involved in splicing[1][3]. However, all evidence indicates that RNU6-1110P is a processed pseudogene, not transcribed into functional RNA, nor associated with protein products, druggability, or human disease[4][5]. - No evidence supports classification as a receptor, enzyme, transporter, or any other canonical drug target. - Thus, it is not a therapeutic target nor should it be included among functionally active molecular targets. If you need information on *functional* U6 snRNA, which is vital for spliceosome activity, or on other spliceosomal components, please clarify.

Other names

RNU6-1110PU6 small nuclear RNA pseudogene 1110U6 snRNA pseudogene 1110