RNA, U6 small nuclear 1137, pseudogene (RNU6-1137P)

RNU6-1137P refers to a specific pseudogene copy of the U6 small nuclear RNA (snRNA) in humans. U6 snRNA is a key structural and catalytic non-coding RNA involved in the spliceosome, the cellular machinery responsible for pre-mRNA splicing[1][3]. However, RNU6-1137P is a *pseudogene* version, meaning it is a non-functional genomic copy generated by retrotransposition, often through LINE-1 (L1)-mediated mechanisms[5]. Pseudogenes like RNU6-1137P are widespread in the genome but do not produce active RNA or protein and do not have known therapeutic target potential or direct roles in disease. They are considered molecular fossils of past genomic activity and may, at most, serve as markers of genomic retrotransposon activity, not as active biomarkers or drug targets[5][4].

Other names

RNU6-1137PRNA, U6 small nuclear 1137, pseudogene

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