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RNA, U6 small nuclear 1140, pseudogene (RNU6-1140P)
- Target
- RNU6-1140P
- Molecular classification
- Pseudogene, Small nuclear RNA-derived pseudogene
01
Overview
RNU6-1140P (RNA, U6 small nuclear 1140, pseudogene) is a human pseudogene affiliated with the U6 small nuclear RNA family. Pseudogenes are segments of DNA that resemble functional genes but typically lack protein-coding ability or canonical biological activity. The ancestral U6 snRNA provides a crucial component for spliceosomal activity (splicing pre-mRNA) in eukaryotes, but this pseudogene does not participate in that function. Some pseudogenes may sporadically produce non-coding RNA transcripts with possible, but largely unestablished, regulatory activity. There is no evidence of RNU6-1140P functioning as a molecular target, nor is it involved in drug response or disease biology as an independent entity.
- Other names
- RNA, U6 small nuclear 1140, pseudogeneRNU6-1140PHGNC:48103NCBI Gene:106480068Ensembl:ENSG00000222449
02
Mechanism of action
Not applicable; no drugs target this pseudogene
03
Biological functions
If transcribed, possible roles as a source for non-coding RNA with regulatory potentialRarely, pseudogene transcripts may participate in regulatory networks by acting as competing endogenous RNAs or serving as sources of small interfering RNAs (siRNAs)Most pseudogenes, including this one, are not known to have established biological roles
04
Disease associations
None for RNU6-1140P specifically.However, the U6 snRNA gene family and some pseudogene-derived lncRNAs have been investigated for possible involvement in cancer and other diseases via regulatory mechanismsNo direct association with human disease is reported for this particular pseudogene
05
Safety considerations
None reported.As a pseudogene, it lacks direct therapeutic or diagnostic utility
06
Biomarkers
None known.RNU6-1140P is not established as a biomarker for disease or therapeutic response
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