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RNA, U6 small nuclear 1157, pseudogene (RNU6-1157P)

Target: RNU6-1157P
Molecular classification: Other (Non-coding RNA pseudogene; not an enzyme, receptor, transporter, etc.)

Overview

RNU6-1157P is a pseudogene derived from the U6 small nuclear RNA gene family, present in the human genome as a result of retrotransposition and genome duplication events[5]. Unlike the canonical U6 small nuclear RNA—which plays an essential role in the spliceosome, catalyzing the removal of introns from pre-mRNA[1][3]—RNU6-1157P does not encode a functional RNA and is not incorporated into the spliceosome[5]. The formation of such pseudogenes is largely due to LINE-1 retrotransposition machinery, and they serve as markers for genome evolution dynamics but lack direct biological, disease, or therapeutic relevance[5]. There are no drugs, disease associations, or clinical markers linked to this specific pseudogene[2][5].

Other names: RNU6-1157PRNA, U6 small nuclear 1157, pseudogene

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