RNA, U6 small nuclear 1162, pseudogene (RNU6-1162P)

RNU6-1162P is a processed pseudogene derived from the U6 small nuclear RNA gene, found in the human genome on chromosome 14 (GRCh38:CM000676.2, location 63,630,678-63,630,781). Like other U6 snRNA pseudogenes, RNU6-1162P arose through retrotransposition events, namely LINE-1 or related mechanisms that integrate RNA intermediates into the genome, often marked by direct repeats and poly(A) tracts. Pseudogenes of snRNAs, including U6, do not generate functional RNAs and generally do not encode mature snRNA products or proteins. Unlike the canonical U6 small nuclear RNA (U6 snRNA), which is an essential noncoding RNA involved in splicing and dynamic catalytic activity in the spliceosome, pseudogenes like RNU6-1162P are considered "dead on arrival": they lack function and are not implicated in disease processes, signaling, or direct therapeutic relevance. Key points: - U6 snRNA pseudogenes are genomic relics with sequence similarity (~77% for some pseudogenes) to genuine U6 RNA, but they do not produce functional RNA molecules and are not used by the cell for splicing. - No protein, receptor, enzyme, transporter, or transcription factor activity is attributed to RNU6-1162P. - The presence of these pseudogenes reflects genomic evolution and historical retrotransposition, not current biological function or therapeutic importance. Conclusion: RNU6-1162P (RNA, U6 small nuclear 1162, pseudogene) is a nonfunctional, processed pseudogene of the U6 snRNA family. It is primarily of genomic interest and has no role as a molecular target, receptor, biomarker, or drug interaction point. Its inclusion in molecular target lists is incorrect; no structured target-related information exists beyond its role as a pseudogene and genomic marker.

Other names

RNU6-1162PRNA, U6 small nuclear 1162, pseudogene

Not applicable (no drugs targeting this pseudogene)