Target intelligence / Profile preview

RNA, U6 small nuclear 1174, pseudogene (RNU6-1174P)

Target
RNU6-1174P
Molecular classification
Other (non-coding RNA pseudogene), Non-coding RNA (pseudogene, not functional snRNA)
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Overview

RNU6-1174P is a **pseudogene** corresponding to U6 small nuclear RNA, a non-coding RNA component of the spliceosome involved in pre-mRNA splicing[4][7]. Pseudogenes such as RNU6-1174P are DNA sequences similar to known genes (in this case, the active gene for U6 snRNA), but they do not produce functional RNA or protein due to mutations, truncation, or other sequence changes[7]. Unlike the canonical U6 snRNA, which plays an essential role in spliceosome catalytic activity and intron removal from pre-mRNA[1][3], RNU6-1174P does not participate in these biochemical processes and is not a recognized drug target or molecular biomarker. Multiple U6 snRNA pseudogenes exist in the human genome, and while their presence reflects the evolutionary importance of U6 snRNA, they themselves are generally functionally inert[3][7][4].

Other names
RNU6-1174PRNA, U6 small nuclear 1174, pseudogeneU6 snRNA pseudogene (generic, not specific to 1174P)
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Mechanism of action

None (no mechanism of action; no drugs target this pseudogene[4])

03

Biological functions

None (pseudogenes typically do not encode functional RNA or protein; no known biological function for RNU6-1174P[4][7])
04

Disease associations

None (not implicated in disease; authentic U6 snRNA has a critical role in splicing, but RNU6-1174P itself is not associated with any disease[4])
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Safety considerations

None (no therapeutic relevance, so no safety issues[4])
06

Interacting drugs

None (no drugs interact with this pseudogene[4])
07

Biomarkers

None (not used as a biomarker[4])

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