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RNA, U6 small nuclear 1233, pseudogene (RNU6-1233P)
- Target
- RNU6-1233P
- Molecular classification
- Pseudogene, Non-coding RNA, Small nuclear RNA pseudogene
01
Overview
RNU6-1233P is a pseudogene of the U6 small nuclear RNA gene, part of a family of non-coding RNAs that play a central role in the splicing of pre-mRNA by assembling into the spliceosome complex[1][3][4][5]. U6 snRNA is highly conserved and essential for eukaryotic gene expression, but pseudogenes such as RNU6-1233P are formed through retrotransposon-mediated genomic duplication and mutation, resulting in genetic elements that resemble the original gene but lack functional activity[4]. These pseudogenes may serve as evolutionary markers for retrotransposon activity but are not biologically active and do not act as therapeutic targets or disease biomarkers[4][5].
- Other names
- RNU6-1233PU6 snRNA pseudogene 1233 (rarely used)
02
Mechanism of action
None (not a druggable target, does not have a mechanism of action)
03
Biological functions
No known biological function (as a pseudogene)The parent gene, U6 snRNA, is involved in pre-mRNA splicing[3][4][5], but the pseudogene does not contribute to this function.
04
Disease associations
None known. Pseudogenes do not encode proteins or functional RNAs and are not implicated in disease processes.
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