RNA, U6 small nuclear 1257, pseudogene (RNU6-1257P)

RNA, U6 small nuclear 1257, pseudogene (RNU6-1257P) is a human pseudogene annotated in reference databases such as HGNC (HGNC:48220), Ensembl (ENSG00000207355), and GeneCards[1][5][7][8][9][10]. It is classified as a processed pseudogene related to the U6 class of small nuclear RNAs (snRNAs), which normally function in the spliceosome complex for pre-mRNA splicing. As a pseudogene, RNU6-1257P does not encode a functional RNA or protein, and there is no evidence linking it to recognized biological functions, disease associations, or drug interactions. It is located on human chromosome 20 (GRCh38: 24,974,171-24,974,280, forward strand)[1][7][8][10]. Like other snRNA pseudogenes, it was likely generated by retrotransposition events but is not considered a therapeutic target or to have mechanistic or biomarker roles in disease[4][6]. RNU6-1257P is a pseudogene, meaning it is a nonfunctional sequence derived from a functional gene or RNA but typically lacking biological activity[1][4][5][10]. No evidence exists that it is druggable, involved in pathology, or used as a biomarker. Standard global and specialist databases (HGNC, Ensembl, GeneCards) uniformly classify it as a pseudogene with no function, role, or target relevance[1][5][7][8][9][10].

Other names

RNU6-1257P