RNA, U6 small nuclear 1338, pseudogene (RNU6-1338P)

**RNA, U6 small nuclear 1338, pseudogene (RNU6-1338P)** is a *pseudogene* related to the U6 small nuclear RNA (snRNA) gene family, located on human chromosome 6[2][4][7]. U6 snRNA itself is a highly conserved non-coding RNA molecule essential in the spliceosome, catalyzing pre-mRNA splicing in the nucleus[1][3]. However, this specific entry, RNU6-1338P, is a processed pseudogene, meaning it does not produce a functional RNA or protein product and is not known to have a biological function, disease role, or therapeutic relevance[5][7]. Pseudogenes of U6, including RNU6-1338P, arise via retrotransposition involving LINE elements and do not encode functional components of the spliceosome[5]. As such, RNU6-1338P should not be considered a drug target, biomarker, or gene of clinical relevance. **Summary of key aspects:** - This gene is a *pseudogene*—a non-functional genomic copy of U6 snRNA with no evidence of biological or therapeutic activity[7]. - There are no described drugs, biological functions, or disease associations tied to this pseudogene. - The canonical U6 snRNA is critical for pre-mRNA splicing as part of the spliceosome, but RNU6-1338P is not involved in this process[1][3][7]. - The gene is listed in gene-centric resources (GeneCards, Ensembl) as a pseudogene, not a coding gene or therapeutic target[2][4][7].

Other names

RNU6-1338PU6 small nuclear RNA pseudogene 1338