Target intelligence / Profile preview

RNA, U6 small nuclear 140, pseudogene (RNU6-140P)

Target
RNU6-140P
Molecular classification
Other (pseudogene), Small nuclear RNA (snRNA, non-coding RNA)
01

Overview

RNA, U6 small nuclear 140, pseudogene (RNU6-140P) is a non-functional pseudogene homolog of U6 small nuclear RNA (snRNA), a highly conserved non-coding RNA essential in RNA splicing as part of the spliceosome[1][3]. U6 snRNA participates in the catalysis of intron removal from pre-mRNA, but pseudogenes like RNU6-140P are typically non-functional genomic elements arising from gene duplication or retrotransposition and do not encode functional snRNA molecules[3]. Pseudogenes are abundant in the human genome; although some pseudogenes have reported regulatory roles, there is no evidence that RNU6-140P is functional, disease-associated, or a druggable target[4]. RNU6-140P is not a functional gene or drug target. There is no evidence of biological, clinical, or therapeutic significance for this specific pseudogene, and it is not considered a protein, receptor, or molecular target in any therapeutic context.

Other names
RNU6-140PU6-140 pseudogeneU6 snRNA pseudogene 140
02

Biological functions

No direct biological function ascribed to this pseudogene itself.U6 snRNA is involved in pre-mRNA splicing as part of the spliceosome[1][3].Pseudogenes in general can sometimes act as decoys for microRNAs or have regulatory functions, but no published evidence assigns any such function to RNU6-140P specifically[4].
03

Disease associations

No direct role in disease is attributed to RNU6-140P.Other pseudogenes have been implicated as regulatory RNAs in various diseases (notably cancer), but there is no data specific to this RNA[4].

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