RNA, U6 small nuclear 191, pseudogene (RNU6-191P)

**RNA, U6 small nuclear 191, pseudogene** (abbreviated as RNU6-191P) is a processed pseudogene derived from the U6 small nuclear RNA (snRNA) gene family. U6 snRNA itself is an essential component of the spliceosome required for pre-mRNA splicing in eukaryotic nuclei. However, RNU6-191P is not functional as it does not produce a functional RNA product; instead, it represents a remnant (“processed pseudogene”) resulting from retrotransposition events facilitated primarily by LINE-1 (L1) elements. Such pseudogenes are highly prevalent in vertebrate genomes and are considered genetic markers for retrotranspositional activity but do not serve any known biological function or therapeutic target role[3][4]. There is no evidence suggesting a disease role, drug interaction, or biomarker utility; therefore, it is not considered an actionable or relevant target in pharmacological or clinical contexts. \n\n**Note:** \n- The molecule is a **pseudogene** and thus **not a protein, receptor, enzyme, transporter, or functional RNA**.\n- There are **no known aliases** beyond its descriptive name and abbreviation.\n- This entry is most relevant for studies of genome evolution and retrotransposition, rather than biology or therapy[4][3].\n- There is **nothing to suggest a therapeutic targeting or clinical importance** for RNU6-191P in the literature.\n- Because it is a non-functional pseudogene, entry as a \"target\" is **incorrect** in the context of drug discovery or biology.

Other names

RNU6-191PU6 snRNA pseudogene 191