RNA, U6 small nuclear 248, pseudogene (RNU6-248P)

RNA, U6 small nuclear 248, pseudogene (RNU6-248P) is a **human genomic pseudogene** corresponding to the U6 small nuclear RNA gene family. U6 snRNA genes encode core components of the spliceosome, but RNU6-248P itself is classified as a **processed pseudogene**—a non-functional genomic locus thought to have arisen from duplication or retrotransposition events, lacking the capacity to encode a functional mature U6 RNA[1][5][9]. While classic pseudogenes are “dead” and nonfunctional, emerging evidence suggests some can be transcribed and exert regulatory effects as non-coding RNAs, for example by acting as competitive endogenous RNAs (ceRNAs) or providing microRNA-binding sites that modulate gene expression[4][8][2]. There is **no direct evidence** that RNU6-248P is expressed or functional, nor is it considered a druggable or therapeutic target. It is primarily annotated as a **genomic feature with no known protein, direct biological activity, or clinical application**[1][9][5].

Other names

RNU6-248P