RNA, U6 small nuclear 293, pseudogene (RNU6-293P)

RNU6-293P is a *pseudogene* version of the U6 small nuclear RNA gene. The canonical U6 snRNA is a highly conserved non-coding RNA involved in the spliceosome machinery that excises introns from pre-mRNA in eukaryotic cells[1][2]. U6 snRNA is evolutionarily crucial and almost universally present in multiple copies and pseudogenes in vertebrate genomes[2]. Pseudogenes like RNU6-293P are non-functional, do not produce a mature snRNA, and do **not participate in splicing** or other cellular activities. They have no recognized biological, disease, or therapeutic roles; nor do they interact with drugs or serve as biomarkers[2]. In contrast, the functional U6 snRNA and its gene copies (e.g., RNU6-1, RNU6-2) are widely used as endogenous controls in molecular biology assays due to their stable and ubiquitous expression[3].

Other names

RNA, U6 small nuclear 293 pseudogeneRNU6-293PU6 snRNA pseudogeneU6 small nuclear RNA pseudogene

None (No mechanism; pseudogene is non-functional[2])