RNA, U6 small nuclear 304, pseudogene (RNU6-304P)

RNU6-304P is a human genomic locus representing a pseudogene of the U6 small nuclear RNA gene family. U6 snRNA is a core member of the spliceosome, the molecular machinery that removes introns from pre-mRNA in the nucleus of eukaryotic cells[1][3]. Pseudogenes such as RNU6-304P arise from ancestral gene duplication or retrotransposition events and typically accumulate mutations that render them non-functional[5]. While some pseudogenes can be transcribed and may have regulatory functions—for example, acting as competing endogenous RNAs (ceRNAs) or "miRNA sponges"—there is no evidence that RNU6-304P possesses a defined function, nor is it established as a therapeutic target or biomarker[4]. It should not be confused with the functional U6 snRNA, which is essential for spliceosomal catalysis[1][3]. If you require information on the functional U6 small nuclear RNA, it is important to note the difference between the functional gene and its numerous pseudogenes, of which RNU6-304P is one example.

Other names

RNU6-304PU6-304 pseudogeneRNA, U6-304 small nuclear, pseudogene

Not applicable