RNA, U6 small nuclear 307, pseudogene (RNU6-307P)

**RNA, U6 small nuclear 307, pseudogene (RNU6-307P)** is a *pseudogene*—a nonfunctional genomic copy—of the gene encoding U6 small nuclear RNA, which is a component of the spliceosomal machinery (complex responsible for pre-mRNA splicing in eukaryotes).[1][3] Pseudogenes like RNU6-307P arise through retrotransposition and contain sequence similarity to functional snRNA genes but lack functional elements, such as promoters, for stable expression or correct processing.[3] Such pseudogenes do not encode proteins or participate in recognized cellular pathways and are considered evolutionary relics rather than active therapeutic targets or biomarkers.[1][3][4] **Key notes:** - This entry refers to a *pseudogene* and not a protein-coding gene, enzyme, receptor, or typical drug target.[1][3] - The canonical U6 small nuclear RNA, from which it derives, is essential for splicing, but pseudogene variants are nonfunctional.[3] - There is no evidence that RNU6-307P is involved in disease or that drugs interact with it. - Pseudogene transcripts (in rare cases) might regulate gene expression, but specific regulatory roles for RNU6-307P are unknown and not documented in current data.[4] If structured data is required for processing, most biomedical and drug development pipelines would designate "is_target: false" for pseudogenes like RNU6-307P.

Other names

RNU6-307PRNA, U6 Small Nuclear 307, Pseudogene

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