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RNA, U6 small nuclear 324, pseudogene (RNU6-324P) is a transcribed pseudogene located in the human genome, corresponding to a non-coding RNA sequence related to the U6 small nuclear RNA (snRNA) gene family[7]. U6 snRNA itself is essential for pre-mRNA splicing in eukaryotes, participating as part of the spliceosome complex, and is highly conserved across species[3]. However, the RNU6-324P sequence does not encode a functional U6 snRNA; instead, it exists as a genetic relic or processed pseudogene with high sequence similarity to genuine U6 snRNA but lacks known biological activity[5][7]. Pseudogenes like RNU6-324P are typically non-functional but may be transcribed at low levels; there is no evidence to date for direct involvement in splicing or any pathophysiological role[2][7]. No drugs, diagnostic biomarkers, disease associations, or safety concerns are documented for this locus.
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