Target intelligence / Profile preview

RNA, U6 small nuclear 348, pseudogene (RNU6-348P)

Target
RNU6-348P
Molecular classification
Pseudogene, Small nuclear RNA (snRNA)-related sequence, Non-protein-coding RNA
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Overview

RNA, U6 small nuclear 348, pseudogene (RNU6-348P) is a member of the U6 small nuclear RNA (snRNA) pseudogene family[1][3][5][7][9]. Pseudogenes are DNA sequences that resemble functional genes but are typically nonfunctional due to disabling mutations or lack of regulatory sequences. RNU6-348P derives from U6 snRNA, which is essential for pre-mRNA splicing as part of the spliceosome; however, the “pseudogene” status signifies RNU6-348P does *not* encode a functional RNA product and is not involved in splicing or other cellular functions[2][3][5][7][9]. Genomic studies categorize such snRNA pseudogenes as molecular fossils of past retrotransposition events and use them as markers for genome evolution, but they lack protein-coding or direct regulatory activity[2][4]. There are no known pharmacological, therapeutic, or diagnostic applications for RNU6-348P, nor is it regarded as a receptor, enzyme, or other classical drug target[3][5][7][9].

Other names
RNU6-348P
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Mechanism of action

None (not a drug target; no known mechanism of action)

03

Biological functions

No direct biological function; classified as a processed pseudogeneParent functional RNA (U6 snRNA) is involved in pre-mRNA splicing via the spliceosome[2][10], but this specific pseudogene is not functional[3][5][7][9]
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Disease associations

No known direct disease association for RNU6-348P[3][5][7][9]Pseudogenes in general may be markers or modifiers in disease, but no specific role is reported for this locus[6]
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Safety considerations

None
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Interacting drugs

None
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Biomarkers

None known for this pseudogene

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