RNA, U6 small nuclear 361, pseudogene (RNU6-361P)

RNU6-361P is a **pseudogene** derived from the U6 small nuclear RNA (snRNA) gene[2][5]. Unlike functional U6 snRNA, which is an essential component of the major spliceosome and participates directly in nuclear pre-mRNA splicing[1][3], RNU6-361P does not code for an active RNA molecule and is generally considered non-functional. U6 snRNA pseudogenes, such as RNU6-361P, occur frequently in vertebrate genomes and typically arise from the retrotransposition or duplication of U6 snRNA genes[3][5]. While some U6 pseudogenes retain sequence similarity to authentic U6 snRNA, they do not participate in spliceosomal activity and do not have characterized biological functions, disease associations, or roles as drug targets[2][5]. \n \nRNU6-361P should not be confused with the functional U6 snRNA, which is crucial for the catalytic steps of pre-mRNA splicing[1][3]. The gene is annotated in human genomic databases (e.g., NCBI Gene 106480574, Ensembl ENSG00000201324)[2].

Other names

RNU6-361P