RNA, U6 small nuclear 366, pseudogene (RNU6-366P)

RNU6-366P (RNA, U6 small nuclear 366, pseudogene) is a non-coding RNA classified as a pseudogene derived from the U6 small nuclear RNA (snRNA) family, not typically considered a direct therapeutic target but possibly involved in regulatory non-coding RNA processes associated with its parental U6 gene. RNU6-366P is a human non-coding RNA pseudogene located on chromosome 14, annotated across standard genomic databases (ENSG00000201097, NCBI 106481294). It is derived from U6 small nuclear RNA, a core component of the spliceosome—the molecular machine responsible for removing introns from pre-mRNA in eukaryotic cells. While U6 snRNA itself is crucial for splicing catalysis and highly conserved, pseudogenes like RNU6-366P do not encode active snRNA molecules, and their direct functional relevance is uncertain. However, pseudogenes may, in some contexts, affect gene expression through various non-coding RNA-mediated mechanisms (e.g., miRNA decoy, double-stranded regulatory RNAs). There is no evidence for RNU6-366P as a direct drug target, receptor, enzyme, or biomarker; it is catalogued to clarify the landscape of non-coding regulatory elements in the genome. Key facts: RNU6-366P is a non-protein-coding pseudogene, not a direct therapeutic target nor known to participate actively in disease pathology or treatment, but belongs to a large family of snRNA pseudogenes that can play indirect roles in gene regulation.

Other names

RNA, U6 small nuclear 366, pseudogeneRNU6-366P

Not applicable; there are no drugs targeting this pseudogene and no direct mechanism of action reported