RNA, U6 small nuclear 428, pseudogene (RNU6-428P)

RNU6-428P (RNA, U6 small nuclear 428, pseudogene) is a **pseudogene** related to the U6 family of small nuclear RNAs (snRNAs)[1][4]. The U6 snRNA is a highly conserved non-coding RNA that functions as a core component of the spliceosome, playing a key role in catalyzing intron removal from precursor messenger RNA in eukaryotic cells[3][5]. However, RNU6-428P itself is classified as a pseudogene, meaning it is a non-functional, typically unexpressed remnant of a duplicated or mutated snRNA gene[1][4]. The human genome contains many such snRNA pseudogenes, which are presumed not to be expressed or to lack any protein-coding or direct catalytic function[4]. There is no evidence that RNU6-428P is a therapeutic target, participates directly in known biological pathways, or is involved in disease mechanisms. **Note:** - This entry is considered "incorrect" as a therapeutic target since pseudogenes, by definition, are not usually expressed or functional in the classical sense, are not standard biological targets, and have no documented modulatory drugs, disease roles, nor reported functional molecular interactions[1][4]. - If you are seeking information on U6 snRNA (the functional gene, not a pseudogene), consult entries for the canonical U6 gene or snRNA, which play proven biological roles in RNA splicing[3][5].

Other names

RNU6-428P