RNA, U6 small nuclear 435, pseudogene (RNU6-435P)

RNU6-435P (RNA, U6 small nuclear 435, pseudogene) is annotated as a **pseudogene** belonging to the U6 small nuclear RNA family[2][4]. Pseudogenes are DNA sequences similar to known genes but are typically non-functional due to mutations or lack of regulatory elements required for expression, and they do not produce functional RNAs or proteins[4]. The parental U6 small nuclear RNA (snRNA) is a non-coding RNA component of the spliceosome critical for pre-mRNA splicing in eukaryotes[1][3], but the RNU6-435P locus itself is not known to have any biological function, disease association, or therapeutic relevance. Multiple copies and pseudogenes of U6 snRNA exist in the genome; most are transcriptionally inactive and do not play a direct role in cellular function[1][5]. There is no evidence for RNU6-435P being a drug target, biomarker, or directly implicated in any pathophysiology[2][4]. **Additional context:** - This is a non-coding, non-functional pseudogene, not a therapeutic target or actionable molecular entity. - There is nothing to suggest it is a misspelling or ambiguous, but its status as a pseudogene renders it biologically and clinically irrelevant as a target. - Functional *U6 snRNA* genes are catalytically essential for splicing, but pseudogene copies such as RNU6-435P are not.

Other names

RNU6-435PRNA U6 small nuclear 435, pseudogeneENSG00000206766HGNC:47398GC18P021800GC00U935046

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