RNA, U6 small nuclear 446, pseudogene (RNU6-446P)

RNU6-446P, or RNA, U6 small nuclear 446, pseudogene, is classified as a **pseudogene** of the U6 small nuclear RNA (snRNA) family. U6 snRNA is a highly conserved non-coding RNA that functions as a core component of the spliceosome, where it facilitates pre-mRNA splicing[1][2][4][5]. However, RNU6-446P does **not** produce functional U6 snRNA and does not participate in spliceosomal activity, as it is a **pseudogene**—a non-functional genomic copy of a gene that may arise through gene duplication or retrotransposition. Pseudogenes are common for U6 snRNA due to its evolutionary importance and high gene copy number, but they lack regulatory elements or have mutations that prevent normal transcription or function[2][5]. There is no current evidence linking RNU6-446P to disease, therapeutic targeting, drug interactions, or known safety concerns.

Other names

RNU6-446P