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Target intelligence / Profile preview
RNA, U6 small nuclear 453, pseudogene (RNU6-453P)
- Target
- RNU6-453P
- Molecular classification
- Other, Pseudogene, Small nuclear RNA pseudogene
01
Overview
RNA, U6 small nuclear 453, pseudogene (RNU6-453P) is a non-protein coding sequence present in the human genome that resembles the U6 small nuclear RNA gene but does not encode a functional transcript. U6 snRNA itself is a critical component of the spliceosome, catalyzing excision of introns from pre-mRNA during post-transcriptional modification in eukaryotic cells[5][3]. The U6 snRNA gene and its related pseudogenes are highly conserved and present in multiple copies across vertebrate genomes, but pseudogenes such as RNU6-453P are typically genomic relics produced by retrotransposition and do not have an established biological or pathological role[4][7].
- Other names
- RNU6-453PRNA, U6 small nuclear 453, pseudogene
02
Mechanism of action
None applicable
03
Biological functions
No direct biological functionparent gene (U6 snRNA) is involved in pre-mRNA splicing
04
Disease associations
None conclusively established for RNU6-453P
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