Target intelligence / Profile preview

RNA, U6 small nuclear 464, pseudogene (RNU6-464P)

Target
RNU6-464P
Molecular classification
Other (pseudogene), Non-coding RNA
01

Overview

RNU6-464P (RNA, U6 small nuclear 464, pseudogene) is a pseudogene derived from the U6 small nuclear RNA (snRNA) gene family. U6 snRNA is an essential non-coding RNA component of the spliceosome, the molecular machinery responsible for removing introns from pre-mRNA in eukaryotic cells[1][3]. U6 snRNA is highly conserved and plays a catalytic role in pre-mRNA splicing, but RNU6-464P is classified as a pseudogene, meaning it is a non-functional remnant that does not produce a stable or active RNA product and is typically not transcribed or translated[4]. While some pseudogenes are known to have regulatory or disease relevance, there is no evidence that RNU6-464P is functional, associated with disease, or a therapeutic target. Notes on accuracy: - RNU6-464P is not an active target or protein; it is a pseudogene and thus not considered a therapeutic target (such as a receptor, enzyme, transporter, etc.). - The entry appears correct as written, but if used as a drug discovery target or protein, its use would be incorrect since it is a non-functional pseudogene and not a functional gene or protein. - Pseudogenes can occasionally regulate parental gene activity by acting as non-coding RNAs, but this is not established for RNU6-464P specifically[4].

Other names
RNU6-464PU6 small nuclear RNA pseudogene 464U6 snRNA pseudogene 464
02

Biological functions

Likely none (for this specific pseudogene, as it is annotated as non-functional)Potential regulatory/epigenetic effect (rare, seen in selected pseudogenes generally but not established for this one)[4]
03

Disease associations

None established for RNU6-464P itselfPseudogenes as a class may have roles in cancer and gene regulation[4]

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