RNA, U6 small nuclear 467, pseudogene (RNU6-467P)

RNA, U6 small nuclear 467, pseudogene (RNU6-467P) is a genomic DNA sequence classified as a pseudogene of the U6 small nuclear RNA (snRNA) family[7]. U6 snRNA, the functional counterpart, is a critical RNA component of the spliceosome, involved in the splicing of precursor messenger RNA (pre-mRNA) in eukaryotes[5][1]. Pseudogenes such as RNU6-467P do not code for functional snRNA due to accumulated mutations or structural deficiencies and are typically regarded as non-coding genomic elements. They can arise through processes such as retrotransposition, often mediated by LINE-1 (L1) elements, resulting in dispersed, non-functional copies throughout the genome[3][8][9]. While most pseudogenes have no known biological function, some can exert regulatory effects on gene expression at the RNA level in rare contexts, though such roles are not described for RNU6-467P specifically[2]. There is no evidence that RNU6-467P acts as a therapeutic target, is implicated in disease biology, interacts with drugs, or serves as a clinically relevant biomarker[7].

Other names

RNU6-467PRNA, U6 Small Nuclear 467, PseudogeneHGNC: 47430NCBI Gene: 106479772Ensembl: ENSG00000276577