RNA, U6 small nuclear 518, pseudogene (RNU6-518P)

**RNU6-518P (RNA, U6 small nuclear 518, pseudogene)** is a member of the U6 small nuclear RNA pseudogene family. U6 snRNA (not the pseudogene) plays a critical role as part of the spliceosome, essential for pre-mRNA splicing in the nucleus of eukaryotic cells[3][5]. However, RNU6-518P itself is a **pseudogene**, meaning it is a genomic sequence similar to the active U6 small nuclear RNA gene but typically non-functional and not transcribed into a functional RNA or protein[1][2][3]. Most pseudogenes like RNU6-518P are presumed to have no biological function and are not considered therapeutic targets[2][1]. While some pseudogenes can be involved in gene regulation or act as sources for non-coding regulatory RNAs, there is no evidence that RNU6-518P plays an active biological or disease-related role, and no drugs specifically target this gene or its product[1][4].

Other names

RNU6-518PU6-518PRNA, U6 small nuclear 518, pseudogene